A Thursday night full of surprises jostled the top four seeds in each region, causing Oregon State, Texas A&M and Duke to slide in the wrong direction.
The selection committee's top-20 reveal last week forced Charlie Creme to reassess some teams at the top of his Bracketology board. But eight of the top 20 teams losing also shook up the bracket.
The 16 are set. Time to catch your breath? Hardly. Here are five questions to ponder before action resumes Saturday.
North Carolina returned to the top of The Associated Press women's basketball poll, just two weeks after surrendering the program's first No. 1 ranking.
Duke chopped a couple points off Tennessee's lead and North Carolina bumped LSU from the No. 3 spot it had held all season in The AP women's basketball poll.
BYU and George Washington joined the AP Top 25 poll.