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Roger Federer was ousted by Kei Nishikori of Japan with a 6-4, 1-6, 6-2 loss Thursday in the third round of the Madrid Open.

Fifth-seeded John Isner beat Ryan Harrison of the United States 7-6 (4) 6-4 in a first-round match at the U.S. Men's Clay Court championships on Tuesday.

Roger Federer beat Denis Istomin of Russia 6-2, 6-3 in their second-round match at the BNP Paribas Open championships on Saturday.

Denis Istomin took advantage of sluggish play by John Isner to eliminate the third-seeded American 6-4, 6-3 on Tuesday in the U.S. National Indoor Tennis Championships.

Novak Djokovic is the master of Melbourne. But what obstacles await him in his quest to hoist the trophy for a third straight time?

Spain defeated Serbia 2-1 to win the Hopman Cup for the fourth time on Saturday.

John Isner withdrew from the Hopman Cup on Thursday because of a right knee injury, ending the American team's chances of reaching the final of the eight-country tournament and handing a championship berth to Spain.

Bernard Tomic upset top-ranked Novak Djokovic 6-4, 6-4 but Australia lost to Serbia 2-1 at the Hopman Cup on Wednesday.

Venus Williams and John Isner led the United States to a 2-1 victory over South Africa at the Hopman Cup mixed team competition Sunday.

Australia beat Germany 3-0 in the Hopman Cup mixed team competition Saturday after Andrea Petkovic had to retire from her singles match with a right knee injury.

Jo-Wilfried Tsonga reached the third round of the Paris Masters with a 6-2, 4-6, 7-6 (2) win over Julien Benneteau on Tuesday.

John Isner of the United States lost to David Goffin 7-6 (2), 4-6, 6-4 Wednesday in the second round at the Valencia Open.

Former No. 1 Lleyton Hewitt beat Juan Monaco of Argentina 6-3, 6-4 in the opening round of the Valencia Open on Monday, ending a 10-match losing run against top-10 opponents.

Roger Federer assured himself the No. 1 ranking for the 300th week of his career by beating Davis Cup teammate Stanislas Wawrinka 4-6, 7-6 (4), 6-0 Thursday in the third round of the Shanghai Masters.

For The Associated Press

Fernando Verdasco of Spain and Philipp Kohlschreiber of Germany reached the second round of the Shanghai Masters with straight-sets victories Sunday.