Can anyone stop Peyton Manning and the Colts? The Steelers will try Monday night in Week 12's best game.
Already 0-2 in the division, the Eagles can ill afford to lose to the Cowboys. Their MNF game is John Clayton's top matchup of Week 10.
There is a lot on the line when the Patriots host the Colts on Monday night in John Clayton's top matchup of Week 9.
With injuries to key players, the Eagles could see their undefeated run end against the Steelers.
The Seahawks' late collapse last week has increased the importance of Sunday's game at New England.
The stingy Jaguars defense will be tested Sunday against the Colts, who have scored 100 points so far.
Sunday night's Chiefs-Broncos showdown is among the weekend's most impressive matchups.
The Vikings and Chiefs bring high-powered offenses into the best matchup of Week 16.
Two of the NFC's best teams -- the Panthers and Cowboys -- meet in the best matchup of Week 12.
The Cowboys will get a big test against the Buccaneers in Week 8's best matchup.
It's a battle of unbeatens as the Colts play host to the Panthers in Week 6's best matchup.
They're not division rivals anymore, but Pittsburgh vs. Tennessee is still Week 4's biggest matchup.
The Broncos host the Raiders on Monday night in Week 3's biggest matchup.
With camps winding down, here's some of the best (Steve McNair) and worst (Green Bay's D) things to watch.
The Broncos and Raiders meet Sunday in a game that has huge playoff ramifications.
Oakland's improved run defense will be put to the test by Ricky Williams and the Dolphins.