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Tristan H. Cockcroft discusses the latest news from around the American Football Conference heading into Week 3.

The Giants may not be playing for only a playoff berth; they may be playing to save Tom Coughlin's job. That's just one of the intriguing subplots of Week 17, writes John Clayton.

The Saints-Cowboys tilt highlights a Week 14 that features numerous games with playoff implications, writes John Clayton.

John Clayton breaks down the best games of Week 15, highlighted by the Colts' playing host to the Bengals on "MNF" in a battle between teams heading in opposite directions.

Colts-Patriots. Manning-Brady. It doesn't get much better than this. Indy's trip to New England highlights an intriguing Week 9, writes John Clayton.

The Rams are 4-1. But are they for real? Sunday's matchup with the Seahawks could answer that question, writes John Clayton in his preview of Week 6.

Forget T.O.'s return to Philly. The Cowboys-Eagles game itself means much more in a week of intriguing divisional matchups that highlight Week 5, writes John Clayton.

John Clayton highlights the best games of Week 2, which is highlighted by a large number of key divisional matchups.

Don't be surprised to see the Eagles and Broncos make some changes on offense in John Clayton's top matchup of Week 8.

John Clayton previews Week 5, with a big matchup between San Diego and Pittsburgh leading the way.

The Ravens and Colts meet in an AFC showdown that will carries significant playoff implications.

The Seahawks finally get a chance to redeem themselves for blowing a late lead against the Rams in Week 5.

The Seahawks' late collapse last week has increased the importance of Sunday's game at New England.

The Packers might need another heroic effort from QB Brett Favre against Denver to make the playoffs.

The Vikings and Chiefs bring high-powered offenses into the best matchup of Week 16.

The Seahawks try to end their road woes in St. Louis in the best matchup of Week 15.