John Clayton's First and Goal: The NFL's marquee rivalry will take a hit if Jim Harbaugh and the 49ers part ways. Plus, playoff race drama negates the rush to expand the postseason field.
John Clayton's First and Goal: Week 6 appears to lack sizzle, but it's a crucial week as division races begin to take shape.
John Clayton's First and Goal: They face tough games, but the Jets and Bills can take big steps in Week 5.
John Clayton's First and 10: The top four teams in each conference can take a big step in Week 13 toward securing a No. 1 seed.
The Packers appear to have what it takes to make a deep playoff run. First they have to turn back an Arizona team that will put up a much tougher fight than it did in Week 17, writes John Clayton.
The feel-good story of last year and the defending Super Bowl champions will square off in Week 1 when the Saints travel to Indianapolis to take on the Colts in the NFL's first game of the season.
Norv Turner gets along with everyone, which is just one reason why he was a good choice as the Chargers' new coach.
The Giants may not be playing for only a playoff berth; they may be playing to save Tom Coughlin's job. That's just one of the intriguing subplots of Week 17, writes John Clayton.
Jeff Garcia and the Eagles can inch closer to the NFC East title when they visit Dallas, and tweak T.O. as well in a game that highlights Week 16, writes John Clayton.
The Saints-Cowboys tilt highlights a Week 14 that features numerous games with playoff implications, writes John Clayton.
John Clayton breaks down the best games of Week 15, highlighted by the Colts' playing host to the Bengals on "MNF" in a battle between teams heading in opposite directions.
The Cowboys-Giants rematch highlights Week 13 and so much has happened since the first time they met, most of it good for Dallas and bad for New York, writes John Clayton.
While Indy-Philly once looked like the marquee matchup, it's a possible Super Bowl preview when the Bears visit the Patriots that highlights Week 12, writes John Clayton.
Things are heating up in the AFC West and the battle between the Broncos and the red-hot Chargers highlights Week 11, writes John Clayton.
The Bears and Giants have emerged at the NFC's best. Their matchup in the Meadowlands highlights an interesting Week 10, writes John Clayton.
Colts-Patriots. Manning-Brady. It doesn't get much better than this. Indy's trip to New England highlights an intriguing Week 9, writes John Clayton.