He's lost his quarterback (Matt Barkley) and his running mate at WR (Robert Woods), but USC junior Marqise Lee is focused on putting up even better numbers than he did during his Biletnikoff-winning sophomore season.
A look at what players and position groups to keep an eye on during USC's spring game on Saturday.
True-freshman running back Justin Davis enrolled at USC early to compete for playing time. Now he's running with the first team.
Biletnikoff Winner Marqise Lee is set as one starting wide receiver for USC, but the battle to find Robert Woods' replacement is one of the most important of the spring.
There wasn't much on the stat sheet from USC fullbacks last season. For the Trojans to be more successful in 2013, sophomores Soma Vainuku and Jahleel Pinner need to be seen more.
Cody Kessler has had to be patient in his two years at USC. But now the sophomore has a shot to accomplish his goal of being USC's starting quarterback.
In looking back at USC's 2012 defense, The Trojans did some good things, but their inability to stop up-tempo spread offense was their downfall.
In looking back at USC's 2012 offense, the Trojans were spectacular at times, but penalties, inconsistency and injuries prevented this unit from truly being great.
USC Trojans running back Tre Madden and defensive end Devon Kennard were poised to be major contributors before season-ending injuries in 2012.
USC can't afford to look past its Sun Bowl matchup with a Georgia Tech team that runs a unique and difficult triple-option offense.
After a slow start to his senior season, USC running back Curtis McNeal is thriving in an increased role, with Notre Dame on tap for McNeal's last game at the Coliseum.
While this year's version of the USC-Notre Dame rivalry has huge implications for the Irish, the Trojans are reduced to playing spoiler.
Wes Horton's father went to UCLA, which gives USC defensive end Wes Horton a great appreciation for playing, and emerging victorious, in the crosstown rivalry game.
The crosstown showdown between USC and UCLA has big implications, as a trip to the Pac-12 title game is at stake.
There will be more than bragging rights on the line when USC and UCLA square off on Saturday. It's reminiscient of 2002, when the Trojans scored a decisive victory.
A big win over Arizona State, led by the beleaguered defense, has USC feeling good heading into a huge showdown with rival UCLA.