Villarreal striker Giuseppe Rossi is expected to spend another ten months on the sidelines.
Roberto Di Matteo has revealed Didier Drogba has no chance of facing Arsenal this weekend and could miss Tuesday's Champions League second leg against Barcelona.
Wolves goalkeeper Wayne Hennessey has been ruled out for around six months after suffering a serious knee injury in the 0-0 draw at Sunderland.
Giuseppe Rossi will miss Euro 2012 and face a further six months on the sidelines after tearing his Anterior Cruciate Ligament (ACL) in training on Friday.
Liverpool midfielder Charlie Adam could miss the rest of the season after suffering a knee ligament injury in the 3-2 defeat against QPR.
Liverpool midfielder Lucas is hopeful he will be fit enough to make his return from injury for the start of next season.
Chelsea's interim boss Roberto Di Matteo will be without John Terry for his side's Premier League meeting with Manchester City.
Chelsea skipper John Terry admits the club's on-field woes drove his incredible injury comeback as he was jogging again only two days after knee surgery.
Sir Alex Ferguson insists Nemanja Vidic is on target to return from his serious knee injury at the start of next season and his comeback will not be rushed.
Everton midfielder Darron Gibson has withdrawn from the Republic of Ireland squad to face the Czech Republic next week because of a knee injury.
Chelsea captain John Terry could be ruled out of action for up to two months after his troublesome knee injury flared up ahead of Tuesday's Champions League clash with Napoli.
Chelsea have announced that John Terry is to undergo an exploratory operation to determine the extent of his knee injury.
Manchester United captain Nemanja Vidic is ahead of schedule in his recovery from a knee injury and could return before the end of the season, according to reports.
Emmanuel Frimpong has been ruled out for the rest of the season after rupturing the anterior cruciate ligament in his right knee in Wolverhampton Wanderers' match at QPR.
Chelsea captain John Terry has been ruled out of Sunday's Premier League clash with Manchester United, having not sufficiently recovered from a knee injury.
Giuseppe Rossi's agent has suggested the striker could consider leaving Villarreal in search of silverware.