UAB 37, Memphis 20
Playing its home games only yards from Churchill Downs, Louisville proved to be nothing short of a sure bet.
Eight Conference USA teams currently rank among the nation's top 53 offenses in yards per game.
Louisville is alone at the top while Southern Miss endured its worst home loss in 13 years.
Miami (Ohio) still needs a wake-up call before each game, but Louisville won't for Memphis.
The Louisville-East Carolina rivalry has featured contentious and occasionally ugly acts from both sides.
New defensive coordinator Mike Cassity has raised Louisville's expectations and instilled a wild aggression in his players.
UAB 35, Memphis 28
He's not getting a lot of attention, but Louisville QB Stefan LeFors is quietly getting the job done.
Coach Tommy West and the Memphis Tigers could be heading for a big season.
A team-by-team look back at the best of the worst of the C-USA this year.
With BCS standings and bowl bids on the line, TCU and Southern Miss meet in a C-USA game like no other.
TCU continues to carry the C-USA banner proudyly and make run it into the BCS.
The face of Conference USA will never be the same.
The biggest game in C-USA isn't this weekend -- it's next Wednesday when TCU meets Louisville.
TCU has survived some close calls to remain in the BCS hunt, but obstacles remain.