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Christopher Harris ponders whether to trust Trent Richardson, Eli Manning, LeSean McCoy and Brandon Lloyd in Week 16, plus he discusses Andrew Luck versus Robert Griffin III, and issues with the Bengals and Cowboys defenses.

The San Francisco 49ers and cornerback Carlos Rogers have reached agreement on a four-year deal worth close to $30 million, a source told ESPN.com senior NFL writer John Clayton

Ken Daube discusses the merits of Victor Cruz and highlights those who are getting the most opportunities to succeed.

Ken Daube explains why Brandon Marshall hasn't cracked the top 20 among fantasy wideouts, and highlights those who are getting the most opportunities to succeed.

49ers coach Jim Harbaugh expects running back Frank Gore to play this week at Philadelphia despite a sprained right ankle that limited him in Sunday's win at Cincinnati.

Media coverage easily could have cost the San Francisco 49ers a road victory against the Cincinnati Bengals in Week 3. That is because NFL coaches rely upon television video feeds when determining which plays to challenge. Networks assign more cam...

Thoughts on the San Francisco 49ers' road victory over the Cincinnati Bengals in Week 3: What it means: The 49ers assured themselves at least a share of first place in the NFC West. They needed until Oct. 31 to win for the second time last season....

49ers wide receiver Braylon Edwards underwent a surgical procedure on his injured right knee and a league source told ESPN NFL Insider Adam Schefter that Edwards is likely to miss three weeks.

Stephania Bell provides the latest injury news on the eve of Week 2, including wideouts Santonio Holmes, Dez Bryant and Hakeem Nicks.

Rounding up Thursday's deals in NFL free agency.

For just the second time ever, the first round of the NFL draft will be the only part of the draft's first day, set for primetime on Thursday night. This year, the Big 12 could have as many as five first-round picks, and five players from the leag...

The St. Louis Rams needed more offensive firepower last season, particularly at wide receiver. That was obvious at critical moments. Left unsaid: The Rams have addressed the position. Since 2008, the team has used three draft choices in the fir...

Kevin Lynch of Niner Insider evaluates Jed York as the San Francisco 49ers' president, outlining the good and bad during York's tenure. Lynch on one of the positives: "York held the line against draft-slot busting contract demands of wide receiver Mi...

The San Francisco 49ers had grand plans for Michael Crabtree when the gifted Texas Tech receiver fell to them in the 2009 NFL draft. Those plans took a detour when a contract dispute kept Crabtree away from the 49ers well into his rookie season. N...

Earlier: Carson Palmer isn't going anywhere just yet, but if the Cincinnati Bengals' quarterback gets his way, he'll be playing elsewhere in 2011. How would he fit in the NFC West? Following up Matt Williamson of Scouts Inc. has studied Pal...

Jim McCormick provides his top picks for Week 1 in the Gridiron Challenge game.