Spikes hopes to return from injury

Linebacker Takeo Spikes hopes to return from a hamstring injury for the 49ers' home game Sunday against Jacksonville.

Week 11 inactives

Tristan H. Cockcroft provides "live" reports and analysis on Week 11 inactives.

49ers WR Bruce sits out vs. Bears

San Francisco 49ers wide receiver Isaac Bruce is inactive against the Chicago Bears with an ankle injury.

Niners' Bruce inactive; Crabtree in

San Francisco 49ers' Isaac Bruce is out vs. the Chicago Bears

Watch out for Willis

...themselves." The Bears do catch a huge break since San Francisco will be without starting cornerback Nate Clements. With Clements out for the second consecutive week, Tarell Brown is scheduled to make his third...

Week 9 NFL inactives

Week 9 inactives

Steelers' no-huddle looms large

Baltimore beat the Broncos by using a smart defensive strategy and a healthy dose of the no-huddle offense. Look for Pittsburgh to use a similar strategy in Denver on Monday night, writes John Clayton.

Titans-49ers Preview

Titans-49ers Preview

Staley, Clements to miss several games

San Francisco 49ers cornerback Nate Clements has undergone a CT scan on his broken right shoulder blade and left tackle Joe Staley had an MRI exam on his sprained right knee to further determine the damage.

Wayne has career-high 12 catches as Colts remain perfect

The Indianapolis Colts won their 16th straight regular-season game and Jim Caldwell became the first rookie coach since the NFL merger to win his first seven games thanks to Sunday's 18-14 victory over San Francisco .

Instant Replay: Austin does it again

Tristan H. Cockcroft looks at the highs and lows from Week 7, including yet another huge game from Miles Austin and a season-ending injury to Leon Washington.

D Up! Injuries taking their toll

Jim McCormick examines the toll injuries have taken on elite IDP performers and reveals who will be directly affected by these, as well as listing some potential replacements from the waiver wire.

...84) completes a 90-yard touchdown-reception in the second quarter as San Francisco 49ers cornerback Nate Clements (22) pursues during an NFL football game against the San Francisco 49ers in San Francisco, Sunday...

Atlanta Falcons wide receiver Roddy White (84) makes a catch as San Francisco 49ers cornerback Nate Clements (22) moves in during the first quarter of an NFL football game, in San Francisco, Sunday...

Will Broncos put Bailey on Moss?

...Nolan, while serving as 49ers head coach last year, oversaw a game plan that had cornerback Nate Clements follow Moss wherever he lined up. Also, the Broncos -- under their prior coaching regime -- had Bailey...