Monday's No. 1 seeds were no surprise. And it wouldn't be shocking to see all four reach the Final Four in Indianapolis.
Might the game's biggest rivalry finally get its next chapter? With no disrespect to the other 62 teams, here's hoping UConn and Tennessee meet up in the national semifinals.
From UConn's chances of repeating to identifying the Huskies' biggest challengers, we break down the biggest questions heading into 2009-10.