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Jim Harbaugh has used the recent run of suspensions on the division rival Seattle Seahawks for performance-enhancing drug infractions as a reminder to his own San Francisco team: Cheating won't be tolerated.

An elevator mechanic was killed Tuesday when he was struck by a counterweight while working in a shaft at the San Francisco 49ers' new stadium, state officials said.

Eric Mangini is back in the NFL -- and back to his coaching roots.

San Francisco 49ers wide receiver Michael Crabtree has undergone surgery for a torn Achillies, a league source confirmed to ESPN senior NFL analyst Chris Mortensen.

The San Francisco Bay Area was awarded hosting rights to Super Bowl L in 2016, while Houston will host Super Bowl LI in 2017, commissioner Roger Goodell announced at the NFL's spring owners meetings in Boston on Tuesday.

Where the Super Bowl will celebrate a half-century of existence will be decided this week by NFL owners.

The future home of the San Francisco 49ers will be called Levi's Stadium.

The San Francisco 49ers have signed guard Adam Snyder to a two-year contract, bringing him back to the franchise after a year with the Arizona Cardinals.

Miami Dolphins CEO Mike Dee said in a television interview Sunday his team won't pay for any renovations to Sun Life Stadium after the Florida Legislature ended its session without passing any funding plan to refurbish the stadium.

Marcus Lattimore saw the 408 area code flash onto his phone and wasn't sure who might be calling him. It was coach Jim Harbaugh from San Francisco 49ers headquarters in Santa Clara. The 49ers were selecting Lattimore with a compensatory pick near the...

The San Francisco 49ers have signed tight end Cameron Morrah to a one-year contract, helping fill a void left by Delanie Walker's departure to the Tennessee Titans.

San Francisco 49ers defensive tackle Justin Smith and linebacker Aldon Smith are working back from offseason surgeries, and general manager Trent Baalke expects each to be at full strength and ready for the start of training camp this summer.

The San Francisco 49ers have signed free agent safety and special teams standout Darcel McBath to a one-year contract, adding depth to the secondary.

Haunted by his Super Bowl loss, 49ers coach Jim Harbaugh is working harder than ever, Ashley Fox writes.

Once the shock of being traded from the Super Bowl champion Baltimore Ravens wore off, Anquan Boldin called Colin Kaepernick to get a feel for the 49ers' young quarterback.

The San Francisco 49ers have signed nose tackle Ian Williams to a two-year contract extension.