Victor Cruz is in a walking boot and is using crutches due to a bruised heel.
Victor Cruz and David Baas, two key New York Giants starters, were both injured during the opening drive of Sunday night's preseason game against the Indianapolis Colts.
Hakeem Nicks plans to return to practice on Tuesday after sitting out the last four practices with a groin injury.
Giants running back Ahmad Bradshaw had another surgery to replace a screw in his right foot.
New York Giants wide receiver Ramses Barden has been diagnosed with a concussion and will not practice Wednesday.
The Giants will be without Jake Ballard and possibly Mario Manningham on Saturday.
New York Giants defensive end Osi Umenyiora is expected to miss at least the next two weeks with a badly sprained ankle, according to sources.
Domenik Hixon has suffered a torn anterior cruciate ligament for the second straight year.
Hakeem Nicks said he does not expect to miss Monday night's game against the Rams after suffering a bone bruise and hyperextending his knee in the season opener.
New York Giants wide receiver Hakeem Nicks is having his knee examined after experiencing swelling on Monday.