Wide receiver David Givens, who has appeared in only five games for the Tennessee Titans since signing a lucrative contract as a free agent in 2006, has undergone a third surgery to address a left knee injury suffered 14 months ago.
Tennessee Titans starting free safety Chris Hope, who missed five games in 2007 finished the season on injured reserve, has undergone neck surgery to address the spinal cord injury that knocked him out of action.
Tailback Reggie Bush, who visited with Dr. James Andrews in Birmingham, Ala., on Monday for a second opinion on his damaged left knee, definitely will not play again in 2007, two league sources told ESPN.com.
Still facing the possibility of season-ending surgery on his right shoulder, San Francisco 49ers starting quarterback Alex Smith is scheduled to go through some light throwing drills Wednesday and Thursday.
Fourth-year cornerback Curtis Deloatch will miss the rest of the Carolina Panthers' season after tearing his left anterior cruciate ligament in Sunday's loss to the Indianapolis Colts, the team confirmed on Monday afternoon.
Rams left defensive end Leonard Little will miss Sunday's game against the Cleveland Browns, and his effectiveness could be affected for the rest of the season by a toe problem that has plagued him for weeks.