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Feisty Philipp Kohlschreiber put an end to John Isner and the American men in New York.
A day after beating Venus Williams in singles at the US Open, Sara Errani and her partner, Roberta Vinci, were knocked out in the second round as the top-seeded team in women's doubles.
After a win in the wind over Varvara Lepchenko, two-time defending champion Serena Williams breaks out the sarcasm to describe her feelings about her US Open run.
We're only on Day 6 at the US Open, but five of the eight seeds already are gone. We rewind the weak week for the fallen favorites.
Petra Kvitova loves Wimbledon, but for some reason, she can't get it together in New York.
Once again, John Isner's trip to Flushing Meadows ended in the third round. Once again, it happened with a loss to Germany's Philipp Kohlschreiber at that stage.
Wimbledon runner-up Eugenie Bouchard edged 30th-seeded Barbora Zahlavova Strycova in three sets to reach the US Open's fourth round for the first time.
Back in the Round of 16 at a major for the first time since 1999, the 32-year-old Mirjana Lucic-Baroni is appreciating tennis like never before as she heads into Sunday's US Open showdown against Sara Errani.
The more he plays, the younger Roger Federer looks, which is a good sign moving forward.
Austrian whippersnapper Dominic Thiem showed why he could be tennis' future.
Simona Halep and Angelique Kerber joined the list of the unfortunate favorites at the US Open.
American tennis took more blows during the first week of the US Open, reinforcing some questions about big names and raising more uncomfortable ones, writes Howard Bryant.
Roger Federer produced one particularly brilliant backhand lob that he celebrated by wagging a finger overhead during a straight-sets, second-round victory at the US Open.
She showed flashes of her old brilliance, but the 34-year-old Venus Williams, who has been busy with doubles, dug a hole and couldn't quite escape in a third-round loss to Sara Errani at the US Open.
Maria Sharapova reached the US Open's fourth round by taking five of the last six games after her opponent, Sabine Lisicki, was warned by the chair umpire about receiving coaching help.
Check out the espnW Photos of the Week from Aug. 22-28, 2014.